Hepatocellular (Liver) Cancer
Adult

Medical Oncology

Useful Management Information

  • Refer patients with new liver lesions (without signs of critical organ dysfunction) with suspected primary liver cancer through local gastroenterology / hepatology pathway for further investigation. For undifferentiated liver lesions (for example suspected metastatic disease from a colorectal or upper gastro-intestinal tract primary site) please through local surgical pathway for further investigation.
  • If the referring clinician organises a biopsy – please ensure a core or excisional biopsy (not a FNA) is performed
  • Depending on their age and comorbidities patients with some stages of primary hepatocellular cancer may be considered for Liver transplantation, surgery or for other treatment techniques either as a bridge to transplantation or as primary treatment, such as TACE, or SBRT. Patients with multifocal disease not suitable for transplant or local therapies may be considered for systemic therapy with monoclonal antibody therapy, or an oral tyrosine kinase inhibitor therapy or suitable clinical trials if available. The referral for initial assessment should be made to the Gastroenterology / Hepatology service, not medical oncology.
  • Serum tumour bio-markers such as CEA, CA19.9 or others should not be used as diagnostic tests, however a serum AFP is indicated for a suspected diagnosis of Hepatocellular carcinoma.
  • For women and men who have not completed their family, fertility preservation needs to be discussed
  • For patients with incurable (metastatic or recurrent) cancer consider the following:
  • documentation of discussions with the patient (and their carers where appropriate) regarding the intent of treatment (anti-cancer therapy to improve quality of life and/or longevity without expectation of cure or symptom palliation), the Women's and men's prognosis and their understanding of their prognosis
  • whether Advance Care Planning (ACP) conversations have been undertaken and their outcome
  • specific patient goals and values that may impact on treatment choices
  • whether the patient has been referred to a palliative or supportive care service
  • Quick reference guide

Minimum Referral Criteria

Does your patient meet the minimum referral criteria?
Category 1 (appointment within 30 calendar days)
  • Patients with a history of cirrhosis of the liver from any cause or history of hepatitis B for monitoring / screening for the development of Hepatocellular carcinoma should be referred to the Gastroenterology / Hepatology service .
  • Patients with suspected primary Liver cancer should be referred to the Hepatology / Gastroenterology team for evaluation and further investigation. Patients are usually then presented in a multi-disciplinary meeting for treatment planning and further referral if required for Medical Oncology input.
  • Patients are usually referred from the MDT meeting after thorough evaluation for appropriate therapies such as Transplant, surgery, Trans-arterial chemo-embolisation, Stereotactic body radiotherapy, Radiologically guided ablation techniques, or Systemic therapies.
  • Patients for Trans-arterial chemo-embolisation therapy prior to surgery or as primary management (usually referred by the Hepatologist or Surgeon after MDT), for optimum care, patient should be seen within 4 weeks.
  • Metastatic or Multifocal hepatocellular cancer (De novo or following prior treatment for known disease) and has tissue confirmation (usually referred by the Hepatologist or Surgeon after MDT)
Category 2 (appointment within 90 calendar days)
  • Transfer of care from another health service
Category 3 (appointment within 365 calendar days)
  • No category 3 criteria

If your patient does not meet the minimum referral criteria

  • Assessment and management information may be found on a range of conditions at HealthPathways
  • If the patient does not meet the criteria for referral but the referring practitioner believes the patient requires specialist review, a clinical override may be requested:
    • Please explain why (e.g. warning signs or symptoms, clinical modifiers, uncertain about diagnosis, etc.)
  • Please note that your referral may not be accepted or may be redirected to another service

Essential Referral Information

  • Detailed history of present signs and symptoms
  • Past medical history/pertinent social history
  • Current medications and allergies
  • Histology report
  • FBC results
  • U&E results
  • LFT results
  • LDH results
  • Liver imaging reports

Additional Referral Information

  • Other available imaging
  • Endoscopy report if available
Last updated 19 February 2025

Send Referrals To

Smart Referrals

Preferred Method
About Smart Referrals

Secure Web Transfer

Not Available

Internal Referrals

Medical Oncology (E-Blueslips)

Fax

(07) 5687 4497

Post

Cancer Referral Centre,
Gold Coast University Hospital
1 Hospital Boulevard
Southport QLD 4215

Enquiries

(07) 5687 2708

Related HealthPathways

No directly related pathways found

Service Availability

Dr Marcin Dzienis
Medical Director Radiation Oncology (ICON Cancer Care)

Facilities

Gold Coast University Hospital

If you would like to send a named referral, please address it to the specialist listed above, who will allocate a suitably qualified specialist to see the patient. Alternatively, you can view a full list of our specialists.

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