Bronchitol Initiation Dose AssessmentAdult
Useful Management Information
The inhalation of bronchitol (mannitol) is intended to improve lung hygiene by correcting impaired mucociliary clearance that is characteristic of cystic fibrosis.
Indications:
- Bronchitol is indicated for the treatment of cystic fibrosis in both paediatric and adult cystic fibrosis populations six years and above, as either an add-on therapy to dornase alfa (pulmozyme) or in patients intolerant to, or inadequately responsive to dornase alfa. Before commencing treatment with bronchitol, all patients must undergo a BIDA to be assessed for bronchial hyperresponsiveness.
Contraindications:
- A baseline FEV1 ≤30% of predicted.
- Hypersensitivity to mannitol or to the gelatin capsule containing mannitol.
- The patient is pregnant and/or breastfeeding.
- Patients below 6 years of age.
- Acute myocardial within 1 week.
- Systemic hypotension or severe hypertension.
- Significant atrial/ventricular arrhythmia.
- Non-compensated heart failure.
- Uncontrolled pulmonary hypertension.
- Acute cor pulmonale.
- Clinically unstable pulmonary embolism.
- History of syncope related to forced expiration/cough.
- Cerebral aneurysm.
- Brain surgery within 4 weeks.
- Recent concussion with continuing symptoms.
- Eye surgery within 1 week.
- Sinus surgery or middle ear surgery or infection within 1 week.
- Presence of pneumothorax.
- Thoracic surgery within 4 weeks.
- Abdominal surgery within 4 weeks.
- Late term pregnancy.
- Active or suspected transmissible respiratory or systemic infection including tuberculosis.
- Physical conditions predisposing to transmission of infections.
Minimum Referral Criteria
Category Category 1 ((appointment within 30 calendar days)) |
|
---|---|
Category Category 2 ((appointment within 90 calendar days)) |
|
Category Category 3 ((appointment within 365 calendar days)) |
|
Essential Referral Information
- Reason for referral - what is the clinical question to be answered by performing the test?
- Current respiratory medications
- Infectious status.
If a specific test result is unable to be obtained due to access, financial, religious, cultural or consent reasons a Clinical Override may be requested. This reason must be clearly articulated in the body of the referral.
Additional Referral Information
- No additional referral information
Send Referrals To
Smart Referrals
Not Available
Secure Web Transfer
Not Available
Internal Referrals
Lung Function Lab (E-Blueslips)
Fax
Post
Lung Function Lab
Gold Coast University Hospital
1 Hospital Boulevard
Southport QLD 4215
Enquiries
Service Availability
Facilities
If you would like to send a named referral, please address it to the specialist listed above, who will allocate a suitably qualified specialist to see the patient. Alternatively, you can view a full list of our specialists.