Useful Management Information
Australian clinical practice guidelines for the diagnosis and management of Barrett's oesophagus and early oesophageal adenocarcinoma (2015) recommended screening endoscopy schedules.
- No dysplasia on endoscopic assessment and Seattle protocol biopsy
- Short (< 3 cm) segment – repeat endoscopy in 3–5 years
- Long (≥ 3 cm) segment – repeat endoscopy in 2–3 years
If there has been previous low-grade dysplasia, see low-grade dysplasia protocol.
Seattle protocol—biopsy of any mucosal irregularity and quadrantic biopsies every 2 cm unless known or suspected dysplasia then quadrantic biopsies every 1 cm.
Indefinite for dysplasia on biopsy
The changes of indefinite for dysplasia on biopsy should be confirmed by a second pathologist, ideally an expert gastrointestinal pathologist. If indefinite for dysplasia is confirmed, then the following endoscopic surveillance is recommended:
- Repeat endoscopy in 6 months with Seattle protocol biopsies for suspected dysplasia (biopsy of any mucosal irregularity and quadrantic biopsies every 1 cm) on maximal acid suppression
- If repeat shows no dysplasia, then follow as per non-dysplastic protocol
- If repeat shows low-grade or high-grade dysplasia or adenocarcinoma, then follow protocols for these respective conditions
- If repeat again shows confirmed indefinite for dysplasia, then repeat endoscopy in 6 months with Seattle protocol biopsies for suspected dysplasia.
Low-grade dysplasia on biopsy
The changes of low-grade dysplasia on biopsy should be confirmed by a second pathologist, ideally an expert gastrointestinal pathologist. If low-grade dysplasia is confirmed, then the following endoscopic surveillance is recommended (or refer to an expert centre for assessment):
- Repeat endoscopy every 6 months with Seattle protocol biopsies for dysplasia (biopsy of any mucosal irregularity and quadrantic biopsies every 1 cm).
- If 2 consecutive 6-monthly endoscopies with Seattle dysplasia biopsy protocol show no dysplasia, then consider reverting to a less frequent follow up schedule.
High-grade dysplasia or adenocarcinoma on biopsy
Referral to a centre that has integrated expertise in endoscopy, imaging, surgery and histopathology
NB: If a patient has been fully investigated 2 years prior to referral, then the referrer and the receiving clinician will need to exercise clinical decision making in triaging and/or value in repeat endoscopy/colonoscopy procedures
Minimum Referral Criteria
Category 1 (appointment within 30 calendar days) |
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Category 2 (appointment within 90 calendar days) |
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Category 3 (appointment within 365 calendar days) |
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Essential Referral Information
- Previous endoscopic procedures (date, report and histology)
If a specific test result is unable to be obtained due to access, financial, religious, cultural or consent reasons a Clinical Override may be requested. This reason must be clearly articulated in the body of the referral.
Additional Referral Information
- No additional referral information
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Southport QLD 4215
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